Ion Chromatography Standards
Apexbio Technology LLC Mepiroxol 6968-72-5 1g
Mepiroxol is a small-molecule compound characterized by its ability to form specific interactions with target proteins It engages in salt bridge interactions with arginine residues (such as Arg-153 and Arg-74) and participates in hydrogen bonding via its hydroxyl group with protein residues like Asp-50 and Gly-96 supporting enhanced binding affinity Researchers utilize Mepiroxol for investigations into protein-ligand interaction mechanisms aiding structural biology analyses and guiding drug-design efforts
Apexbio Technology LLC DTNB 69-78-3 1g
DTNB (69-78-3) is a biochemical reagent that reacts specifically with free sulfhydryl (-SH) groups It is utilized to quantitatively detect thiol groups in biological samples DTNB exerts its activity by undergoing disulfide bond cleavage upon interaction with free thiols leading to the formation of a colored derivative 5-thio-2-nitrobenzoate (TNB) which is measurable by spectrophotometry at 412 nm Based on these properties DTNB is widely applied in the quantification of reduced glutathione (GSH) and assessment of thiol levels in tissues blood and cultured cells enabling studies of oxidative stress redox state and thiol-reactive drug screening
Apexbio Technology LLC Taurine 107-35-7 1g
Taurine (CAS 107-35-7) is a sulfur-containing -amino acid abundantly present in animal tissues It modulates a range of physiological processes including osmoregulation calcium signaling and membrane stabilization Taurine acts as a neuromodulator in the central nervous system and influences neurotransmitter regulation ion channel function and cellular antioxidant defense mechanisms It is frequently utilized in biomedical research to investigate its roles in cardiovascular function neuroprotection and metabolic regulation as well as to explore its impact on cellular homeostasis under physiological and pathological conditions
Thermo Scientific Dionex Nitrite Standard (1000mg/L), 125mL
For Use With Routine anion determinations | Type: Standard | Standard Components Nitrite 1000mg/L | Volume 125 mL
Apexbio Technology LLC Oxipurinol 2465-59-0 1g
Oxipurinol (CAS 2465-59-0) is a small molecule inhibitor of xanthine oxidoreductase (XO) an enzyme integral to purine metabolism As the principal active metabolite of allopurinol oxipurinol functions as a noncompetitive XO inhibitor contributing significantly to the pharmacological effects observed with allopurinol therapy In vitro studies indicate that both allopurinol and oxipurinol demonstrate XO inhibition and exhibit free radical scavenging properties with evidence of cardioprotective effects independent of XO activity In vivo oxipurinol administration has been shown to reduce vascular free radical production in hypercholesterolemic animal models Its pharmacokinetic profile is characterized by predominant renal clearance Oxipurinol is widely utilized in research exploring oxidative stress cardiovascular physiology and disorders of purine metabolism
Apexbio Technology LLC Risedronate 105462-24-6 1g
Risedronate (CAS 105462-24-6) is a small-molecule inhibitor targeting farnesyl pyrophosphate (FPP) synthase It is designed to inhibit this enzyme in the mevalonate pathway thereby reducing osteoclast prenylation and function Risedronate exerts its biological activity primarily through selective binding to hydroxyapatite surfaces in bone leading to decreased osteoclastic activity and suppressed bone resorption Based on these pharmacological properties Risedronate holds research potential in the study of osteoclast biology metabolic bone disorders osteoporosis and bone remodeling processes
Apexbio Technology LLC Chenodeoxycholic Acid 474-25-9 1g
Chenodeoxycholic Acid is a small-molecule agonist targeting the farnesoid X receptor (FXR) It is designed to selectively activate FXR thereby regulating critical signaling pathways involved in bile acid homeostasis lipid metabolism and cholesterol regulation Chenodeoxycholic Acid exerts its biological activity primarily through FXR-dependent modulation of transcriptional pathways Based on these pharmacological properties Chenodeoxycholic Acid holds research potential in the investigation of hepatic metabolism mechanisms cholesterol balance metabolic disorders and FXR-mediated gene expression in various physiological and pathological conditions
Apexbio Technology LLC DL-Panthenol 16485-10-2 1g
DL-Panthenol (CAS 16485-10-2) is an alcohol derivative of pantothenic acid (vitamin B5) It is designed to support epithelial cell metabolism by serving as a prodrug that is converted to pantothenic acid and subsequently integrated into Coenzyme A (CoA) DL-Panthenol exerts its biological activity primarily through its conversion into pantothenic acid in epithelial cells enhancing CoA-dependent metabolic processes This promotes fibroblast proliferation and re-epithelialization during wound repair No specific IC50/EC50 values or experimental models are provided Based on these pharmacological properties DL-Panthenol holds research potential in studies of epithelial regeneration wound healing and inflammation modulation in dermatology
Apexbio Technology LLC PDE5-IN-7 139756-21-1 1g
PDE5-IN-7 (CAS 139756-21-1) is a selective inhibitor of phosphodiesterase 5 (PDE5) functioning by impeding PDE5 enzymatic activity and thereby reducing the hydrolysis of cyclic guanosine monophosphate (cGMP) This results in elevated intracellular cGMP levels In biochemical assays PDE5-IN-7 demonstrates potent inhibition of PDE5 with an IC50 of approximately 5 nM while displaying significantly lower potency against PDE1 (IC50 300 nM) Due to its selectivity and potency PDE5-IN-7 is valuable for investigating cGMP-mediated signaling vasorelaxation mechanisms and pathways involved in cardiovascular physiology
Apexbio Technology LLC Pyriproxyfen 95737-68-1 1g
Pyriproxyfen (CAS 95737-68-1) is a small-molecule inhibitor targeting insect juvenile hormone receptors It is designed to interfere with hormone-mediated developmental signaling thereby disrupting endocrine-regulated metamorphosis in insect larvae Pyriproxyfen exerts its biological activity primarily through binding to juvenile hormone receptors impeding physiological maturation and reproduction cycles in target arthropod populations In laboratory experiments pyriproxyfen demonstrates inhibitory activity with IC50 values ranging from approximately 0 1 to 10 M depending on insect species and experimental conditions Based on these pharmacological properties pyriproxyfen holds research potential in agricultural pest management and public health applications involving vector-borne diseases transmitted by arthropods
Apexbio Technology LLC Congo Red 573-58-0 1g
Congo Red (CAS 573-58-0) is a small-molecule inhibitor targeting the vesicular glutamate transporter (VGlut) It is designed to modulate glutamate storage and release thereby influencing synaptic transmission Congo Red exerts its biological activity primarily through selective non-covalent interaction with -sheet-rich structures such as those found in amyloid fibrils Based on these properties Congo Red holds research potential in the detection and qualitative assessment of amyloid deposits in tissue sections characterization of amyloidosis-related samples plant and fungal cell wall amyloids and lipopolysaccharide staining in Gram-negative bacterial outer membranes for biomedical and microbiological studies
THERMO SCI 3P AIG PARTS & ACCESSORIES CHROMELEN CAFF 10ML 6X10ML
NC0396871 CHROMELEN CAFF 10ML 6X10ML
Apexbio Technology LLC Lisinopril 76547-98-3 1g
Lisinopril (CAS 76547-98-3) is a small molecule inhibitor of angiotensin-converting enzyme (ACE) By blocking ACE activity lisinopril reduces the formation of angiotensin II which diminishes vasoconstriction and aldosterone-mediated sodium and water retention resulting in reduced peripheral vascular resistance This compound is frequently utilized in biomedical research to investigate the pathophysiological mechanisms of hypertension congestive heart failure and cardiovascular disorders as well as to develop and validate preclinical pharmacological models related to ACE inhibition
Apexbio Technology LLC Beaucage reagent 66304-01-6 1g
Beaucage reagent (CAS 66304-01-6) is a small molecule compound utilized for its ability to modulate DNA integrity by targeting enzyme-mediated processes involved in DNA cleavage Experimental studies demonstrate that Beaucage reagent induces DNA double-strand breaks thereby affecting cellular pathways related to cell cycle regulation and apoptosis Owing to these properties this reagent serves as a valuable tool for applications in gene editing and genetic studies supporting a range of molecular biology research efforts that require controlled manipulation of genomic DNA
Apexbio Technology LLC Cefdinir 91832-40-5 1g
Cefdinir (91832-40-5) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit bacterial cell wall synthesis thereby obstructing the final transpeptidation step of peptidoglycan formation Cefdinir exerts its biological activity primarily through PBP binding-mediated inhibition of cell wall biosynthesis In microbiological assays Cefdinir demonstrates antibacterial inhibition with reported IC50 values ranging from approximately 0 5 to 4 g/mL against susceptible bacteria Based on these pharmacological properties Cefdinir holds research potential in antibacterial susceptibility testing determination of minimum inhibitory concentrations (MIC) and investigation of antibiotic resistance mechanisms