Ion Chromatography Standards
Apexbio Technology LLC Cephalexin monohydrate 23325-78-2 1g
Cephalexin monohydrate (CAS 23325-78-2) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit PBPs thereby impairing bacterial cell wall synthesis and compromising cell wall integrity Cephalexin monohydrate exerts its biological activity primarily through disruption of bacterial cell wall cross-linking leading to cell lysis In in vitro studies cephalexin monohydrate demonstrates inhibitory activity with reported MIC values ranging from 0 5 g/mL to 32 g/mL depending on bacterial species and experimental conditions IC50 values are dependent upon specific bacterial strains evaluated Based on these pharmacological properties cephalexin monohydrate holds research potential in antimicrobial susceptibility testing bacterial resistance studies and related microbiological assays
Apexbio Technology LLC Progesterone 57-83-0 1g
Progesterone (57-83-0) is a steroid hormone that modulates reproductive processes by specifically interacting with its nuclear receptors It is designed to regulate embryo implantation and endometrial physiology thereby influencing estrogenic signaling and target gene expression in reproductive tissues Progesterone exerts its biological activity primarily through attenuation of estrogenic signaling affecting genes such as Egr1 In in vitro studies progesterone demonstrates the ability to restrict cell proliferation pathways in melanoma models including B16F10 mouse cells and BLM human cell lines Additionally progesterone regulates mammary carcinoma progression via RANKL-dependent activation of signaling components such as GLI-1 Based on these pharmacological properties progesterone holds research potential in studies of hormonal regulation reproductive biology cancer progression and neuroprotection
Apexbio Technology LLC Perindopril 82834-16-0 1g
Perindopril (CAS 82834-16-0) is an inhibitor of angiotensin I-converting enzyme (ACE) widely used in biomedical research By blocking ACE activity Perindopril suppresses the formation of angiotensin II a peptide involved in vasoconstriction and angiogenesis In cancer studies Perindopril has demonstrated the ability to inhibit tumor growth and angiogenesis in head and neck squamous cell carcinoma models While it does not significantly affect cell proliferation in vitro it reduces VEGF mRNA expression and promoter activity at concentrations as low as 1 M In vivo Perindopril has been shown to suppress tumor growth and lower blood pressure without altering heart rate supporting its application in oncology and cardiovascular research
Apexbio Technology LLC Oxymatrine 16837-52-8 1g
Oxymatrine (CAS 16837-52-8) is a quinolizidine alkaloid extracted from Sophora flavescens It has been shown to modulate multiple cellular pathways associated with fibrosis and neurodegeneration including inhibition of TGF- 1-mediated signaling and reduction of pro-inflammatory cytokine expression Oxymatrine exhibits antifibrotic and neuroprotective properties in various experimental models It is also extensively studied for its antiviral activity against hepatitis B virus and has been applied in traditional Chinese medicine for hepatitis management This compound is valuable for investigating mechanisms of fibrosis neuroprotection and viral pathogenesis
Apexbio Technology LLC L-(-)-α-Methyldopa (hydrate) 41372-08-1 1g
L-(-)- -Methyldopa (hydrate) (CAS 41372-08-1) is a small molecule that functions as an agonist selective for 2-adrenergic receptors Through its sympatholytic properties it diminishes central adrenergic outflow resulting in decreased blood pressure This compound is widely utilized in biomedical research to investigate mechanisms of adrenergic signaling and to model antihypertensive pharmacological effects Its ability to modulate neurotransmitter pathways makes it a useful tool for studies of cardiovascular regulation and central nervous system pharmacodynamics
Apexbio Technology LLC Levodopa 59-92-7 1g
Levodopa (59-92-7) is a small-molecule precursor of dopamine It modulates dopaminergic signaling pathways thereby influencing neurotransmission and associated neuronal functions Levodopa exerts its biological activity primarily through enzymatic decarboxylation by aromatic L-amino acid decarboxylase within dopaminergic neurons yielding dopamine In in vitro assays levodopa demonstrates cholinergic receptor antagonism with reported IC50 values typically ranging 10 30 M depending on specific cellular and experimental conditions Based on these pharmacological properties levodopa holds research potential in studies of dopaminergic signaling neuronal plasticity motor function modulation preclinical Parkinson s disease models and stroke recovery investigations
SPEX CERTIPREP LLC 3P SULFATE 500ML 1000PPM
(HPS by Zeptometrix) Sulfate (from Na2SO4) IC Std 1000 ug/mL in H2O Exp Date: 18 Months
Apexbio Technology LLC Candesartan Cilexetil 145040-37-5 1g
Candesartan Cilexetil (CAS 145040-37-5) is a selective angiotensin II receptor antagonist that inhibits the binding of angiotensin II to the AT1 receptor subtype By blocking this interaction it modulates pathways involved in vascular tone and blood pressure regulation In preclinical research Candesartan Cilexetil has been investigated for its capacity to attenuate the progression of pulmonary fibrosis modulate host response in viral infections and facilitate skin wound healing These properties support its utility in studies of cardiovascular pathophysiology fibrotic disease mechanisms viral infection dynamics and tissue repair processes
Apexbio Technology LLC Fluocinonide 356-12-7 1g
Fluocinonide (CAS 356-12-7) is a synthetic glucocorticoid steroid targeting intracellular glucocorticoid receptors (GR) It is designed to modulate gene transcriptional activity thereby regulating the production and release of inflammatory cytokines and mediators in the inflammatory response pathway Fluocinonide exerts its biological activity primarily through binding to glucocorticoid receptors and forming receptor-ligand complexes which influence cellular and molecular inflammatory signaling cascades Based on these pharmacological properties fluocinonide holds research potential in studying pathophysiological mechanisms of inflammatory skin conditions evaluating topical corticosteroid metabolism and absorption and facilitating investigations focused on dermatological inflammatory responses
Apexbio Technology LLC Diuron 330-54-1 1g
Diuron is a small-molecule inhibitor targeting electron transport within chloroplasts It is designed to interfere with photosynthesis by suppressing electron transfer thereby affecting cellular energy metabolism via reduced ATP and NADH synthesis Diuron exerts its biological activity primarily through inhibition of electron transfer in chloroplasts In experimental studies in animal models dietary administration of Diuron at elevated concentrations is associated with increased occurrence of urothelial carcinoma Based on these pharmacological properties Diuron holds research potential in studies of photosynthetic biochemical pathways cellular energy regulation and chemical-induced carcinogenesis